Like many of the Swords suit, the 10 of Swords does carry an unpleasant connotation, but it is also not necessarily the end of the world. When the 10 appears, however, it is a clear signal to be careful about where you put your trust.
In general, when the 10 comes up in relation to a question as to whether you can believe what a person is telling you, or trust that a situation is stable, this is a pretty clear answer of "no." However, try to bear in mind that whenever a door closes, another door opens. You are being guided to a situation that is better for you. Trust yourself and trust in the universe.
Career & Employment
The appearance of this card may signal that your work situation is about to come to an end. Your best bet is to get your ducks in a row and think through what you will do if you do indeed lose your job, for any reason. You may have been treated badly by someone. Don't waste your time and precious energy plotting revenge. Just get on with the next phase of your life. If you're looking for work, a potential position that you'd pinned your hopes on may not come through. Above all, don't give up.
Love & Relationships
In relation to love questions, this is sadly not a good omen. Something about the love situation you are in is not quite right. Ask yourself a lot of questions, accept reality, don't close your eyes to the truth. You cannot force someone to love you or to behave respectfully. If you have recently met someone new (and are looking for love,) keep looking. The contenders you've met so far are not who they seem to be.
Finances & Income
In terms of money, you may be facing a disappointment. This is not under any circumstances a time to gamble, but it is a time to take stock. If money has taken a downturn for you, or someone you trusted has not come through, be careful not to beat yourself up. This is not the end of the world. Try to think logically and rationally. What now?
Mental & Physical Health
Your health situation may not be as good as you had hoped. Be careful in what healer and what methods you put your trust. Don't be afraid to call on all healing energies you can think of; angels, the universe, ancestors, your higher power, God, whatever you can relate to. There is much more to life than what meets the eye, and miracles happen every day. However, you have to be sure that you are doing your part. What can you do, right now, to better your health situation? Consider alternative healing methods
You may finally let go of a long, deeply held spiritual belief that has actually been standing in your way. Again, you must be careful where you put your trust in terms of spiritual leaders who may seem to have your best interests at heart but who may actually be looking only to line their pockets. You make a break from the past. This is actually a good thing, although it may be somewhat painful.